6. Indianapolis, IN
This city sports way more than just really fast racecars. With major retailers like Finish Line and HHGregg located here, it’s not hard to see why the unemployment rate is just 4.3 percent for 45-54-year-olds (down more than three percentage points from the year before). But the city makes way more than shoes and appliances – it’s a hotbed for pills. Pharmaceutical giant Lilly is based here (the name behind Prozac), employing more than 11,500 workers across the state at an average salary of more than 150K. Talk about an anti-depressant.
